Non-Invasive Test for the Creutzfeldt - Jakob Disease


Published Date : Aug 07, 2014

After conducting a few experimental tests, it was observed that nasal cells and also the cells in urine samples can help detect the mad cow disease in humans. The human category of the mad cow disease is known as Creutzfeldt-Jakob disease. 

According to the New England Journal of Medicine, this may help the diagnosis and prognosis of the Creutzfeldt-Jakob disease. The advantage is that the patients will not need to undergo any invasive procedures for diagnosis of this syndrome. This disease is quite rare as only one in a million get affected by it. But there are some areas which are prone to the Creutzfeldt-Jakob disease, like England where several years ago, a certain form of this disease had affected people who had consumed fouled beef. 

A defective protein called prion causes this disease by disfiguring the healthier versions of the same protein. The brain gets affected the most, and ultimately the brain tissue develops perforations making it look like a sponge and proves to be fatal. 

Diagnosing this disease can be a little challenging because it has no specific symptoms. The symptoms can vary from loss of memory to paranoia. The foolproof methods for diagnosis are taking brain cell samples and testing the spinal fluid, both of which are invasive techniques. 

The non-invasive techniques as discussed earlier, are less time consuming as compared to the traditional techniques. The urine test, however, worked for those who suffered from the Creutzfeldt-Jakob disease’s variant which was caused by the consumption of cattle meat that was contaminated. Different types of diagnosis tests need to be carried out for the variants of this disease.