Discovery of Genes Associated with Increasing Risk of Coronary Heart Disease to Boost Treatment Hopes


Published Date : Mar 15, 2016

The researchers at the British Heart Foundation have found out that two new genes are responsible for increasing the risk of coronary heart disease. Changes in the DNA code that alters a gene named ANGPTL4 are associated with reduced risk of coronary heart disease. Errors in another gene called SVEP1 have been linked to rise in the risk of coronary heart disease. Coronary heart disease leads to sudden heart attacks, resulting to death. The research findings are being termed as very important from the perspective of finding new therapies.

Demand for Defibrillators Rise with Growing Prevalence of Coronary Heart Diseases

Currently, defibrillators are being increasingly used to save patients suffering from sudden cardiac arrest. A defibrillator depolarizes critical part of a heart muscle, thereby restoring the normal heart rhythm. The chances of survival of patients affected by sudden cardiac arrest rise if cardiopulmonary resuscitation (CPR) and defibrillation are administered within 5 to 12 minutes of cardiac arrest. 

According to a research paper published in the Dove Medical Press, countries in the Middle East and Africa are witnessing a rising prevalence of coronary heart diseases owing to hypertension, diabetes, smoking, dyslipidemia, and sedentary lifestyle. Smoking rates across most of the countries in these regions have shot up and hence, tobacco consumption has been marked as a major factor contributing to the rise in patients suffering from sudden cardiac arrests. Patients in these regions are suffering from myocardial infarction at a younger age, on an average, compared to patients residing elsewhere. All these factors have contributed significantly towards the growth of the defibrillator market in these regions. In the U.A.E, the growing awareness about the utility of defibrillators and various government initiatives have boosted the demand or defibrillators.