Published Date : Aug 20, 2018
Researchers from the University of Copenhagen have found a way to identify the protein that is responsible for cellular memory transmission by dividing cell. These researchers used the new technique which helped them to understand the development of one cell to the whole body. Cells divide and create new life throughout life. But, the procedure and how the cell remember whether they are developing in skin, liver or intestinal cells.
Their new technique - SCAR-seq - helps to give new vision into epigenetic cellular memory. They are able to address the procedure of storing epigenetic information in histone proteins and transferred in DNA and divided in two. This study is published in the scientific journal Science.
It is the first time that researchers are able to see which protein are on the new DNA strands and which are copied from cell division. Based on this information, the researchers are now able to investigate how protein-based information is inherited and propagated to daughter cells.
Anja Groth, a professor at the Biotech Research & Innovation Center, University of Copenhagen, and co-author of the study said this is the first study which is directly linked to the transfer of epigenetic information on histones with the duplication of genetic information. Inside the human cell, DNA is surrounded by the histone proteins. They form a different structure known as chromatin. When a cell divides the structures forms accurately as earlier. This chromatin mainly stores epigenetic information and affects which genes are to be expressed. Based on this information cells in the human body to control which genes will be on or off.