In a new research finding at San Diego School of Medicine, University of California researchers have found the difficulty to use stem cells for liver and pancreatic problems. The research, however, can lead to new treatments for diseases such as Type 1 Diabetes.
The researchers found out, the chromosomes that are found in laboratory stem cells open slowly in the similar sequential manner it does in embryonic development. They further added, some of the chromosomal region need to reach the open state to be able to respond to added factors of growth and become pancreatic or liver cells.
The researchers also added, their ability to create liver and pancreatic cells from stem cells falls behind advancements for other stem cells. As a consequence, researchers have not been able to do more such as new drugs testing for stem cells derived pancreatic and liver cells. The researchers further added they have come to an interesting finding, if the stem cells are used for specific cells then it should be predicted in some way how the chromosomes and cells would respond to the growth factors.
The focus of the researchers have been studying stem cells for treatment of diseases as those can be altered into hundreds cell types. The research team further added, it could take up to seven steps of adding growth factors at different times all of which is carefully orchestrated for the stem cells to be coaxed to obtain the desired cell type.