Addisons Disease Therapeutics Market - Global Industry Trend Analysis 2012 to 2017 and Forecast 2017 - 2025


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Addison’s Disease Therapeutics Market: Snapshot 

Over the past few decades, the Addison’s disease therapeutics market has made rapid strides on the back of application of some novel approaches. These approaches have aimed at improving the long-term outcome of the treatments and quality of life of patients. The advent of novel exogenous steroid formulations is an important case in point. Advances in adrenocortical stem cell biology in the recent decade have set the pace for innovation in the Addison’s disease therapeutics market. There has also been extensive research on understanding the science behind novel approaches. This is reinforcing the potential of the market. Lately, regenerative therapies in Addison's disease have attracted considerable attention of researchers and the medical fraternity in general. In particular, immunomodulatory and regenerative medicine approaches have shown great potential. Also bearing some significance in the market are drug classes such as Glucocorticoid and mineralocorticoid replacement therapy. 

Growing incidence of pediatric adrenal insufficiency in patients in various parts of the world in recent times have brought new dimension to the Addison’s disease therapeutics market. Drug makers are making efforts in developing therapeutics in autoimmune adrenal insufficiency. Moreover, the increasing awareness of patients about ways of preventing acute adrenal crisis bodes well for the Addison’s disease therapeutics market. In this respect, primary care providers have played an increasingly promising role. Further, growing numbers of promising drugs in the pipeline, especially in developed countries such as the U.S., are catalyzing the prospects. 

Addison’s disease is a hormonal disorder characterized by inadequate secretion of certain hormones such as cortisol (glucocorticoid) and aldosterone (mineralocorticoid) by adrenal gland. Cortisol manages glucose level and is also helpful in suppressing immune response. Aldosterone regulates the sodium and potassium level in the body. This disease condition is also called as adrenal insufficiency and occurs in people of all age groups. Addison’s disease affects both sexes equally. In some cases it can be life threatening as well. This disease is mainly caused by damage to the adrenal cortex that may be due to autoimmune disorders including chronic thyroiditis, Graves’ disease, myasthenia gravis and pernicious anemia; infectious diseases such as tuberculosis, HIV and fungal infections; tumor and hemorrhage into the adrenal gland. In major developed countries, tuberculosis has been identified as one of the major factors for Addison’s disease and accounts for nearly 20% of all adrenal insufficiency cases. Most common symptoms associated with this hormonal disorder include weight loss, tiredness, loss of appetite, muscle weakness, low blood pressure, paleness, chronic diarrhea, nausea, vomiting and darkening of the skin in some places.

Addison’s disease is usually diagnosed by a blood test (for potassium level, cortisol level and serum sodium) or CT scan. In some cases abdominal X-ray is also performed in order to confirm the illness. Its treatment involves the replacing of insufficient hormones with the laboratory developed hormones that mimic the functions of natural ones. Hydrocortisone tablet is given orally in order to replace cortisol while fludrocortisone acetate is recommended for aldosterone insufficiency. The market for Addison’s disease therapeutics is primarily dominated by generic drugs such as cortisone, fludrocortisones and prednisone whose patent exclusivity had expired since long.

The market for Addison’s disease therapeutics is expected to grow worldwide owing to globally rising incidence of Addison’s disease and rigorous research and development leading to introduction of new products. According to sources from Elsevier, Inc., the annual incidence rate of Addison’s disease has been found 5-6 per million of population while the prevalence rate is 40-110 per million of population. A recent epidemiological study indicates that the incidence of Addison’s disease is increasing year on year. In September 2012, ViroPharma, Inc. launched a novel drug called Plenadren in Denmark for treating adrenal insufficiency. This novel drug was granted a European marketing Authorization by the European Commission in November 2011. Denmark became the first country in the whole European Union to offer a new treatment option to people suffering from Addison’s disease in over the last 50 years. Increasing awareness among patients and physicians regarding the disease is also expected to play a key role in driving the market growth during the forthcoming years.

In terms of geography, the market for Addison’s disease therapeutics has been segmented into North America, Europe, Asia-Pacific and Rest of the World (RoW). Reimbursement of expenses related with the Addison’s disease treatment by Medicare and Medicaid in the United States is one of the major factors driving the market growth in the North American region. Also the fact that patients and physicians of this region being more aware than the patients and physicians of other regions is driving the market growth in the region. Some of the major research institutes and companies engaged in the development, manufacturing and marketing of drugs and injectables for the Addison’s disease treatment are University of Wurzburg, Aarhus University, Oregon Health and Science University, University Hospital Tubingen, Shire plc, DuoCort AB and HaEmek Medical Center.

MRR.BIZ has been compiled in-depth market research data in the report after exhaustive primary and secondary research. Our team of able, experienced in-house analysts has collated the information through personal interviews and study of industry databases, journals, and reputable paid sources.

The report provides the following information:

  • Tailwinds and headwinds molding the market’s trajectory
  • Market segments based on products, technology, and applications
  • Prospects of each segment
  • Overall current and possible future size of the market
  • Growth pace of the market
  • Competitive landscape and key players’ strategies

The main aim of the report is to:

  • Enable key stakeholder’s in the market bet right on it
  • Understand the opportunities and pitfalls awaiting them
  • Assess the overall growth scope in the near term
  • Strategize effectively with respect to production and distribution

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