Biologicals In Oncology Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2019



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Biological therapy is defined as use of living organisms and substances derived from organism or synthetically produced version of such substances in laboratories to treat the disease condition. Some of the biological therapies for cancer involve vaccines or bacteria to stimulate the body’s defense system to act against cancer cells. The biologicals in oncology market is majorly differentiated into three major segments, on the basis of biological, on the basis of development stage and on the basis of pathway mapping involved in cancer therapy investigation. On the basis of type of biologicals available in market, the market is further segmented as:
  • Monoclonal antibodies
  • Cytokine therapy
  • Vaccine therapy
  • Adoptive T-cell therapy
  • Oncolytic virus therapy
  • Gene therapy
  • DNA oligonucleotide therapy
  • RNA oligonucleotide therapy
There are at least 880 companies and their partners involved in developing around 1500 drugs in developmental projects in cancer for the treatment of 132 tumor and cancer types. The market for biologicals in oncology is going to experience rapid growth as the prevalence of cancer all over the world is increasing. But the major restraint involved in this market is the fear from the side effects of the treatments as predicted by clinical trials of the drugs as the therapies involving biological lead to pain, swelling, redness, itchiness, soreness and rashes at the site of infusion. Biologicals which provoke an immune system response can even lead to risk of severe or even fatal hypersensitivity reactions. The other major restraint in the market is the high cost involved in the development and clinical trials of the therapies. On the basis of development stage of drugs, the market is segmented as follows:

  • Marketed 
  • Registered 
  • Pre-registration
  • Phase III clinical trials
  • Phase II clinical trials
  • Phase I clinical trials
  • Preclinical trials
  • No Data
  • Suspended
  • Ceased
The pathways that the drug follows are also important for the market of biologicals in oncology. Pathway is the chain of protein in the cell that communicates a signal from receptor to the surface of DNA in nucleus of cell. This pathway consists of many proteins, such as mitogen-activated protein kinases (MAPK) and extracellular signal regulated kinases (ERK), these proteins help in communication. When one of the protein is mutated, it leads to “on” or “off” position. The therapy that reverse the “on” or “off” situation is further investigated for cancer therapies. The biologicals in oncology market are divided into four categories on the basis of pathways involved in cancer therapy investigation which are as follows: 
  • BioCarta pathways
  • KEGG pathways
  • NCI-Nature pathways
  • NetPath pathways
North America currently leads the market for biologicals in oncology followed by Europe and Asia-Pacific due to awareness about therapies and support from government to improve healthcare conditions. The market of Asia-Pacific region is driven by Japan. Among the marketed and registered therapies concerning biologicals in oncology, the market of monoclonal antibodies therapy and vaccine therapy generates a major part of revenue for the market because it increases chances of uptake of cancerous tissue by increasing t1/2 in plasma, protects normal tissues, improves uptake into cancer cells, enables escape from lysosomes and provides long term drug release for low dose drugs. The market players and institutes which are involved for clinical trials and manufacturing biological include Astex Therapeutics, F. Hoffmann - La Roche, Limited, Prometheus Therapeutics and Diagnostics, Northwest Biotherapeutics, Merck and Company, Immunovative Therapies, NewLink Genetics Corporation, Limited, The University of Bologna Medical School, Rui Jin Hospital, Klinikum der J.W. Goethe Universitaet, National Institute of Mental Health, Peking University People's Hospital and Hadassah University Hospital among others.

This research report analyzes this market depending on its market segments, major geographies, and current market trends. Geographies analyzed under this research report include 
  • North America 
  • Asia Pacific 
  • Europe
  • Rest of the World  
This report provides comprehensive analysis of 
  • Market growth drivers 
  • Factors limiting market growth
  • Current market trends 
  • Market structure
  • Market projections for upcoming years 
This report is a complete study of current trends in the market, industry growth drivers, and restraints. It provides market projections for the coming years. It includes analysis of recent developments in technology, Porter’s five force model analysis and detailed profiles of top industry players. The report also includes a review of micro and macro factors essential for the existing market players and new entrants along with detailed value chain analysis. 

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