Colorectal cancer also known as bowel cancer, rectal cancer, colorectal adenocarcinoma and colon cancer, is a type of cancer that results from uncontrolled growth of cells of rectum or colon (part of large intestine). Sometimes, cellular over-growth of appendix is also termed as colorectal cancer. Changes in bowel habit, rectal bleeding, anemia and weight loss are some of the common symptoms that a patient suffers from colorectal cancer. Colorectal cancer usually occurs in a person due to change in lifestyle that, results in shift in diet pattern to fast food. Sometimes, genetic disorders can also result in colorectal cancer. The disease generally starts from inner lining of bowel and it spreads into muscular layers, if left untreated at the early stage.
Colorectal cancer can be diagnosed through various in-vitro colorectal cancer screening tests that include fecal occult blood tests, colorectal cancer (CRC) DNA screening tests and biomarker tests. Fecal occult blood tests can be further segmented as guaiac fecal occult blood stool tests, immuno-FOB Agglutination tests, lateral flow immuno-fecal occult blood tests and immuno-FOB test ELISA. Similarly, colorectal cancer (CRC) DNA screening tests can be categorized as methylated gene testing and panel DNA tests. Biomarker tests include tumor M2-PK stool test (2-in-1 quick test) and transferrin Assays. Among all the aforementioned tests in-vitro screening tests for colorectal cancer, fecal occult blood tests market accounts for the largest share of the total in-vitro colorectal cancer screening tests market. The large market size of fecal occult blood tests is due to its large usage for diagnosing colorectal cancer that increases its demand in the market. Also, this test is efficient in diagnosing the disease precisely in less time duration unlike other in-vitro colon screening tests.
Various tests are in pipeline assessments that are able to overcome drawbacks of all the above mentioned screening tests for colorectal cancer include BST1 CRC assay, PanC-Dx, ColoGuard, oncolite CR, cologic, MiR-21 test and colon cancer BEC Test. Some other pipeline screening tests include metabiomics CRC Test, colon MarCare Plex, measure fecal occult blood test, colox, genomictree methylated DNA test, CRC bacterial signature assay, ExiQon MicroRNA test, CRC breath test and Epi proColon. It has been opined by various scientists across the globe that these pipeline tests are expected to diagnose the presence of colorectal cancer accurately.
The market for in-vitro colorectal cancer screening tests is expected to grow at a noteworthy CAGR from 2013 to 2019. This growth is attributed to rise in number of patients suffering from colorectal cancer across the globe. It has been stated by the National Cancer Institute (NCI) that colon cancer is amongst the second largest cause of cancer death and is the third most diagnosed cancer in the U.S. The American Cancer Society (ACS) has estimated that nearly 136,830 people are expected to be diagnosed with colon cancer by the end of 2014 in the U.S. and around 50,310 people will die by the end of the same year in the U.S. Similarly, increasing research and development initiatives by various companies for developing diagnosing tests throughout the globe will further propel the growth of in-vitro colorectal cancer screening tests.
Some of the major players operating in this market include Abbott Laboratories, Beckman Coulter, Inc. Companion Dx, Epigenomics AG, ExiQon, Merck KGaA,, Randox Laboratories, Siemens Healthcare, VEDALAB, Sysmex Corporation, Signature Diagnostics, R-Biopharm AG, MDx Health Quest Diagnostics, Alere and Kyowa Medex Co., Ltd. among other significant players.
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