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Methyl acetoacetate also known as acetoacetic methyl ester, methyl-3-ketobutyrateiron sulfate, acetoacetic acid or acetoacetic acid methyl is a methyl ester of acetoacetic acid. It is a colorless clear liquid with a fruity odor. It reacts with acids and liberates heat along with alcohols. Reaction with alkali metals and hydrides generates flammable hydrogen. Methyl acetoacetate is soluble in water (44 wt %) and is completely soluble in alcohol, ether and ether acetate. Methyl acetoacetate is manufactured by the reaction of methanol with beta-ketone (1,3-diketone) in presence of a catalyst. Other raw material used in production includes acetyl ketene, methane and ethyl acetoacetate among others. Methyl acetoacetate acts as a copromoter in resins and other compounds. Moreover, it is also used as a chemical intermediates in various end-user industries such as pharmaceutical, agro chemicals and others. Additionally, methyl acetoacetate is also used in as an intermediate in manufacturing of dyestuffs and organic pigments. Methyl acetoacetate is primarily used as intermediate in manufacturing of polymers and other materials. It is used in production of amino acids, antibiotics and aminopyrine among others.
The market for methyl acetoacetate was mainly driven by end-user industries such as pharmaceutical, agrochemicals and solvents among others. Methyl acetoacetate is used as a pharmaceutical intermediate in formulations such as amoxyciline, dipyridamole and antipyrine among others. In agrochemicals, methyl acetoacetate is used as an intermediate for manufacturing primiphos, hymexazole and mevinphos among others. It is also used in perperation of vitamins such as A, E and B1. Methyl acetoacetate is used as a starting material in the production of cyclic compounds such as coumarine and pyrazole. It is used as starting material in production of aceto- acetic esters. In perfume and cosmetic industry, it used as an solvent for fragrances. Moreover, methyl acetoacetate is used in the production of azo dyes, masking isocynates in enamels, lacquers and plastics among others. However, due to environmental regulations and raw material issues the market is likely to be sluggish over the forecast period. Moreover, methyl acetoacetate may be harmful on ingestion or inhalation and causes eye and skin irritation.
In terms of demand, Asia Pacific was the leading and the fastest growing region for methyl acetoacetate in 2013. The demand was huge due to increasing demand from pharmaceutical and agrochemicals industry in this region. China had the highest demand for methyl acetoacetate in Asia Pacific region. Other Asia Pacific countries such as South Korea, India, and Japan are likely to provide better opportunity for methyl acetoacetate market owing to increasing consumption from agrochemicals and perfume end-user industry in these regions. Asia Pacific was followed by North America. Increasing demand from agrochemicals market is driving the demand for methyl acetoacetate in this region. U.S. had the largest demand for methyl acetoacetate owing to huge demand from agrochemicals industry. Europe had the third-largest demand for methyl acetoacetate market in 2013. Increasing demand for methyl acetoacetate from perfumery products, pigments, dyestuff and pharmaceuticals has been driving the market for methyl acetoacetate in Europe. Western Europe is one of the largest consumers of methyl acetoacetate in this region. Rest of the World market is anticipated to show positive outlook for the methyl acetoacetate market in near future. Brazil, Argentina and South Africa are anticipated to be the fastest growing market in this region.
Some of the key manufacturers in the methyl acetoacetate market are Lonza Group, Laxmi Organics, Eastman Chemicals and TCI Development Co. Ltd. among others.
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